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MilliporeSigma™ Phosphodiesterase 7A1, Human, Recombinant Protein, S. frugiperda

Catalog No. 52475110U Shop All MilliporeSigma Products
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52-475-110U 10 U
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Catalog No. 52-475-110U Supplier MilliporeSigma™ Supplier No. 52475110U
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Description

Full-length, recombinant, human phosphodiesterdase 7A1 (PDE7A1) expressed in S. frugiperda insect cells using a baculovirus expression system. PDE7A1 is required for T-cell activation induced by the costimulation of CD3 and CD28 receptors. Increased PDE7A1 correlates with a decrease in cAMP, increased IL-2, and increased cell proliferation. Supplied as a partially purified preparation of catalytically active enzyme useful for inhibitor and activator assays.
TRUSTED_SUSTAINABILITY

Specifications

Formulation In 150mM NaCl, 10mM Tris, 0.1% NP-40, pH 8.3.
Quantity 10 U
Source S. frugiperda
Immunogen Phosphodiesterase 7A1
Storage Requirements Following initial thaw, aliquot and freeze (−70°C).
Regulatory Status RUO
Species Human
Recombinant Recombinant
Form Liquid
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