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MilliporeSigma™ PKG, Iα, Bovine Lung, Protein

Catalog No. 5395784UG Shop All MilliporeSigma Products
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53-957-84UG 4 μg
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Description

Native PKGIα purified from bovine lung. PKG is involved in regulation of smooth muscle relaxation, platelet function, and cell division. PKG is activated by binding of cGMP to regulatory subunits within the holoenzyme, but in contrast to PKA, the activation of PKG does not invlove physical dissociation of catalytic from the regulatory domains. The activated enzyme phosphorylates target proteins at serine and/or threonine residues that are found within the recognition motif, Arg-Lys-Arg-Ser-Arg-Ala-Glu.
TRUSTED_SUSTAINABILITY

Specifications

Concentration Concentration on Label
Formulation In 150mM NaCl, 25mM β-mercaptoethanol, 10mM K2HPO4, 1mM EDTA, 12% sucrose, pH 6.8.
Quantity 4 μg
Immunogen PKG, Iα
Storage Requirements Following initial thaw, aliquot and freeze (−70°C).
Regulatory Status RUO
Species Bovine
Recombinant Native
Form Liquid
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