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MilliporeSigma™ Tissue Plasminogen Activator, Human, Protein

Catalog No. 612200100UG Shop All MilliporeSigma Products
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Catalog No. Quantity
61-220-0100UG 100 μg
61-220-01MG 1 mg
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Catalog No. 61-220-0100UG Supplier MilliporeSigma™ Supplier No. 612200100UG
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Description

Native tissue plasminogen activator from a human melanoma cell line. A serine protease that contains a single chain of 527 amino acids. Binds to fibrin via lysine binding sites at its amino terminus and activates bound plasminogen. Cleaves plasminogen to form active plasmin, the proteolytic enzyme that dissolves clots. Reported to be involved in neurite outgrowth, regeneration, and migration. Plays an important role in excitotoxin-induced neuronal degeneration.
TRUSTED_SUSTAINABILITY

Specifications

Formulation Lyophilized from 100mM PBS, 3.5mg/mL L-arginine, 0.001% Tween™-80 Detergent.
Preparation Method Reconstitute with diH2O to a final concentration of 1mg/mL (e.g., 100μg should be reconstituted in 100μL).
Purification Method SDS-PAGE
Quantity 100 μg
Immunogen Tissue Plasminogen Activator
Storage Requirements Following reconstitution, aliquot and freeze (−20°C). Stock solutions are stable for up to 6 months at −20°C.
Regulatory Status RUO
Species Human
Recombinant Native
Form Lyophilized
Purity or Quality Grade ≥95%
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