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MilliporeSigma™ Upstate p300, HAT Domain Recombinant Enzyme 
Recombinant GST-fusion protein corresponding to amino acids 1066-1707 of human p300.
Manufacturer: MilliporeSigma™ 14418
Description
EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CBP (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CBP can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.This product(s) resides on a Fisher Scientific GSA or VA contract. If you are viewing this page as a nonregistered user, the price(s) displayed is List Price. To view your GSA or VA contract pricing, log in using your account number, or become a registered user by contacting one of our Customer Service teams. You can also view your contract price by searching for this item(s) on GSA Advantage. To place an order, contact Fisher Scientific Customer Service.
Specifications
| Histone Acetyltransferase Assay (HAT) | |
| 50μg | |
| Expressed in E. coli | |
| -20°C for up to 6 months from the date of receipt |
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