Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 734250

Tocris Bioscience™ Emetine dihydrochloride
GREENER_CHOICE

Catalog No. 734250
Change view
Click to view available options
Quantity:
50 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
73-425-0 50 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Catalog No. 73-425-0 Supplier Tocris Bioscience™ Supplier No. 7342/50
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika

Emetine is a RNA polymerase inhibitor. It inhibits SARS-CoV-2 replication (EC50 = 460 nM) and in combination with Remdesivir (Cat. No.7226) synergistically inhibits the viral yield of SARS-CoV-2 by 64.9%. Emetine attenuates hCoV-OC43, hCoV-NL43, SARS-CoV, MERS-CoV, and MHV-A59 in vitro with EC50 values in the low micromolar range. It also inhibits replication of a broad range of RNA and DNA viruses, including influenza, ebolavirus and HIV-1. Emetine potently inhibits ZIKV replication in vitro (IC50 = 52.9 nm) and suppresses ZIKV viral load in vivo. Anti-inflammatory, antiviral, antimalarial, antibacterial and anti-amebic.

Specifications

Chemical Name or Material (2 S,3 R,11 bS)-3-Ethyl-1,3,4,6,7,11 b-hexahydro-9,10-dimethoxy-2-[[(1 R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-2 H-benzo[a]quinolizine dihydrochloride
CAS 316-42-7
Quantity 50 mg
Target RNA/DNA Polymerase Inhibitors
Molecular Formula C29H40N2O40.2 HCl
Purity 0.98
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.