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EMPA, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
This item is not returnable. View return policy
680590-49-2
C23H26N4O4S
454.545
KJPHTXTWFHVJIG-UHFFFAOYSA-N
empa,7ma,n-ethyl-2-6-methoxypyridin-3-yl-2-methylphenyl sulfonyl-amino-n-pyridin-3-ylmethyl ethanamide,d02mdc,n-ethyl-2-6-methoxy-3-pyridinyl 2-methylphenyl sulfonyl amino-n-3-pyridinylmethyl-acetamide,n-ethyl-2-6-methoxy-pyridin-3-yl-toluene-2-sulfonyl-amino-n-pyridin-3-ylmethyl-acetamide,n-ethyl-2-6-methoxy-pyridin-3-yl-toluene-2-sulphonyl-amino-n-pyridin-3-ylmethyl-acetamide,n-ethyl-2-6-methoxypyridin-3-yl-2-methylphenyl sulfonylamino-n-pyridin-3-ylmethyl acetamide
9981404
N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonylamino]-N-(pyridin-3-ylmethyl)acetamide
CCN(CC1=CN=CC=C1)C(=O)CN(C2=CN=C(C=C2)OC)S(=O)(=O)C3=CC=CC=C3C
This item is not returnable. View return policy
680590-49-2
C23H26N4O4S
454.545
KJPHTXTWFHVJIG-UHFFFAOYSA-N
empa,7ma,n-ethyl-2-6-methoxypyridin-3-yl-2-methylphenyl sulfonyl-amino-n-pyridin-3-ylmethyl ethanamide,d02mdc,n-ethyl-2-6-methoxy-3-pyridinyl 2-methylphenyl sulfonyl amino-n-3-pyridinylmethyl-acetamide,n-ethyl-2-6-methoxy-pyridin-3-yl-toluene-2-sulfonyl-amino-n-pyridin-3-ylmethyl-acetamide,n-ethyl-2-6-methoxy-pyridin-3-yl-toluene-2-sulphonyl-amino-n-pyridin-3-ylmethyl-acetamide,n-ethyl-2-6-methoxypyridin-3-yl-2-methylphenyl sulfonylamino-n-pyridin-3-ylmethyl acetamide
9981404
N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonylamino]-N-(pyridin-3-ylmethyl)acetamide
CCN(CC1=CN=CC=C1)C(=O)CN(C2=CN=C(C=C2)OC)S(=O)(=O)C3=CC=CC=C3C

Highly potent and selective OX2 antagonist; brain penetrant

Highly potent, selective OX2 receptor antagonist (IC50 values are 2.3 nM and 1900 nM for OX2 and OX1 respectively). Displays negligible or no inhibition of a panel of 80 receptors. Blocks orexin-B- and orexin-A-invoked calcium mobilization in hOX2-expressing CHO cells (IC50 values are 7.9 nM and 8.8 nM respectively); reverses orexin-B-induced hyperlocomotion in mice. Brain penetrant.

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Quantity 10mg
Formula Weight 454.54
Percent Purity >98%
Chemical Name or Material EMPA

Recommended Storage : Store at -20°C