Invitrogen™ EMR4 Polyclonal Antibody

Catalog No.	Quantity
PIPA5102076	100 μL

Catalog No. PIPA5102076 Supplier Invitrogen™ Supplier No. PA5102076

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total EMR4.

FIRE is a 689 amino acid protein that maps to human gene EMR4. FIRE is also known as EGF-like module-containing mucin-like hormone receptor-like 4 and is a member of the the G protein-coupled receptor 2 family, LN-TM7 subfamily. The epidermal growth factor-transmembrane seven (EGF-TM7) family are proteins that express EGF-like domains at their extracellular N-terminus coupled to a classical seven-transmembrane (TM7) cassette. FIRE is believed to mediate the cellular interaction between myeloid cells and beta cells. FIRE is a membrane bound, multi-pass protein that is proteolytically cleaved into two subunits, an extracellular alpha subunit and a seven-transmembrane subunit. FIRE contains one GPS (G protein-coupled receptor proteolytic cleavage site) domain and two EGF (epidermal growth factor)-like domains, the second of which mediates the interaction with the putative ligand.

Specifications

• Antigen: EMR4
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: ADGRE4P
• Gene Accession No.: Q86SQ3
• Gene Alias: ADGRE4P; adhesion G protein-coupled receptor E4, pseudogene; EMR4; EMR4P; FIRE; GPR127; PGR16
• Gene Symbols: ADGRE4P
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human ADGRE4P(Accession Q86SQ3), corresponding to amino acid residues K129-L179.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 326342
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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