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Endonuclease VIII, 2000 U, G-Biosciences
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Catalog No. S001140
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Catalog No. S001140 Supplier G-Biosciences Supplier No. 7862274
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Description

Endonuclease VIII from E. coli has dual functions as an N-glycosylase and an AP-lyase. It removes damaged pyrimidines from double-stranded DNA to create an AP site. The AP-lyase activity then cleaves at this site, resulting in a 5′ phosphate and a 3′ phosphate.

  • This enzyme targets damaged bases like thymine glycol and uracil glycol. Unlike Endonuclease III, which only has β lyase activity, Endonuclease VIII also exhibits δ lyase activity, enabling it to address a broader range of DNA damage.

Specifications

Packaging Vial
Enzyme Endonuclease
Sensitive to Heat Inactivation Yes
Product Type Endonuclease VIII
Research Category DNA Repair
Product Line Thermo Scientific
Form Liquid
Product Title
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