Invitrogen™ Endothelin A Receptor Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA3065

Catalog No. PIPA3065

Description

PA3-065 detects Endothelin Receptor A from human, mouse, and rat samples. PA3-065 has been successfully used in Western blot, immunocytochemistry, and immunohistochemistry procedures. By western blot, this antibody detects a 46kDa protein corresponding to mouse Endothelin Receptor A.

This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: Endothelin A Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EDNRA
• Gene Alias: Ednra; Endor; Endothelin A; endothelin A receptor; endothelin receptor subtype A; endothelin receptor type A; endothelin type A receptor; endothelin-1 receptor; endothelin-1-specific receptor; ETa; ET-A; ETAR; ET-AR; ETA-R; ETRA; G protein coupled receptor; G protein-coupled receptor; Gpcr10; G-protein coupled receptor 10; hET-AR; MFDA; RGD1559432
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: Conc. Not Determined
• Formulation: whole serum with 0.02% sodium azide
• Gene Accession No.: P25101, P26684, Q61614
• Gene Symbols: EDNRA
• Immunogen: COOH-terminal amino acids of mouse ETA (408-427) KNQEQNNHNTERSSHKDSMN coupled to KLH.
• Regulatory Status: RUO
• Gene ID (Entrez): 13617, 1909, 24326
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid