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Invitrogen™ Endothelium Monoclonal Antibody (EN4)
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Catalog No. 01671414
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Catalog No. Quantity
01-671-414 1 mL
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Catalog No. 01-671-414 Supplier Invitrogen™ Supplier No. MA135359
  • $630.00
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Description

Mouse Monoclonal Antibody

This antibody stains all human blood vessels including brain microvessels. Both large and small vessels are equally reactive. The EN4 antigen is preserved in endothelial cells in culture unlike the PAL-E antigen which is lost. It stains strongly murine fibroblasts transfected with the human CD31 gene. On surface-iodinated Jurkat T cells it recognizes the 130 kD CD31 antigen. EN4 also binds to guinea-pig and cat endothelium, but not to rabbit, bovine, sheep, dog, rat or mice endothelial cells. No other structures in the skin, heart, kidney, tonsils or spleen are stained with this antibody.

The endothelium is the layer of thin specialized epithelium, comprising a simple squamous layer of cells that line the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall (simple squamous epithelium). Endothelial cells line the entire circulatory system, from the heart to the smallest capillary. These cells reduce friction of the flow of blood.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Endothelium
Applications Flow Cytometry, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone EN4
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and 0.02% sodium azide
Gene Alias Endothelial cell marker; Endothelial cells; Endothelium Cell Antigen-1; Pan endothelial cells
Host Species Mouse
Immunogen Proprietary Immunogen.
Purification Method Purified
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Feline, Guinea Pig
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

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