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Bioassay Systems EnzyFluo™ MMP-1 Inhibitor Assay Kit, For evaluation of drugs and screening of potential inhibitors to MMP-1.
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Catalog No. 5000144370 Shop All Bioassay Systems Products
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MATRIX METALLOPROTEINASE-1 or MMP-1 (EC 3.4.24.7) is a Ca2+– and Zn2+-dependent, interstitial collagenase that plays a role in the remodeling of the extracellular matrix of tissues. MMP-1 is up-regulated in metastatic cancer cells and in rheumatoid arthritis. BioAssay Systems’ EnzyFluo™ MMP-1 Inhibitor Assay Kit uses a quenched synthetic substrate. Upon digestion by MMP-1, the substrate is cleaved, which abolishes the quenching of the fluorescence label. The fluorescent fragment is measured at λex/em = 490/520 nm. Inhibition is determined by the decrease in fluorescence.

Catalog No. 50-001-44370 Supplier Bioassay Systems Supplier No. EIMP1100
May include imposed supplier surcharges.
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MATRIX METALLOPROTEINASE-1 or MMP-1 (EC 3.4.24.7) is a Ca2+– and Zn2+-dependent, interstitial collagenase that plays a role in the remodeling of the extracellular matrix of tissues. MMP-1 is up-regulated in metastatic cancer cells and in rheumatoid arthritis. BioAssay Systems’ EnzyFluo™ MMP-1 Inhibitor Assay Kit uses a quenched synthetic substrate. Upon digestion by MMP-1, the substrate is cleaved, which abolishes the quenching of the fluorescence label. The fluorescent fragment is measured at λex/em = 490/520 nm. Inhibition is determined by the decrease in fluorescence.

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