EPB41L2/4.1G Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A301425AT

Catalog No. 50-156-0358

Description

The recommended shelf life for this product is 1 year from date of receipt.

The 4. 1 gene family encodes a group of multifunctional cytoskeletal proteins (4. 1R, 4. 1G, 4. 1N and 4. 1B), which are predomitly expressed in the nervous system. 4. 1G is a protein that stabilizes spectrin-actin interactions and is associated with hereditary elliptocytosis. Red blood cell 4. 1, designated 4. 1R, is a multifunctional protein that is essential for maintaining erythrocyte shape and membrane mechanical properties. Both 4. 1R and 4. 1G are distributed in a unique pattern in the cerebellum and are believed to modulate the membrane mechanical properties of neuronal cells by promoting fodrin/actin association. 4. 1N and 4. 1B, designated EPB41L1 and EPB41L3, respectively, are strongly expressed in the brain. Antibodies to 4. 1N have been reported to detect multiple forms, each enriched in postsynaptic density preparations relative to brain homogenate. Antibodies to 4. 1B have been reported to detect two forms.

Specifications

• Antigen: EPB41L2/4.1G
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: O43491
• Gene Symbols: EPB41L2
• Immunogen: Between 575 and 625
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: EPB41L2
• Gene Alias: EPB41L2; 4.1-G; erythrocyte membrane protein band 4.1-like 2; RP3-324N14.1; DKFZp781D1972; DKFZp781H1755; OTTHUMP00000040262; erythrocyte membrane protein band 4.1 like-protein 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2037
• Content And Storage: 4° C
• Form: Liquid