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Invitrogen™ EPB41L2 Polyclonal Antibody
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Catalog No. PIPA5121222
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PIPA5121222 100 μL
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Catalog No. PIPA5121222 Supplier Invitrogen™ Supplier No. PA5121222
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Rabbit Polyclonal Antibody

Positive test controls include: U-87MG, HeLa, Jurkat, SKOV3. The target is usually found in the following locations: Cell membrane, Cytoplasm, cytoskeleton. Immunogen sequence: MTTEVGSVSE VKKDSSQLGT DATKEKPKEV AENQQNQSSD PEEEKGSQPP PAAESQSSLR RQKREKETSE SRGISRFIPP WLKKQKSYTL VVAKDGGDKK EPTQAVVEEQ VLDKEEPLPE EQRQAKGDAE EMAQKKQEIK VEVKEEKPSV SKEEKPSVSK VEMQPTELVS KEREEKVKET QEDKLEGGAA KRETKEVQTN ELKAEKASQK.

The 4.1 gene family encodes a group of multifunctional cytoskeletal proteins (4.1R, 4.1G, 4.1N and 4.1B), which are predominantly expressed in the nervous system. 4.1G is a protein that stabilizes spectrin-actin interactions and is associated with hereditary elliptocytosis. Red blood cell 4.1, designated 4.1R, is a multifunctional protein that is essential for maintaining erythrocyte shape and membrane mechanical properties. Both 4.1R and 4.1G are distributed in a unique pattern in the cerebellum and are believed to modulate the membrane mechanical properties of neuronal cells by promoting fodrin/actin association. 4.1N and 4.1B, designated EPB41L1 and EPB41L3, respectively, are strongly expressed in the brain. Antibodies to 4.1N have been reported to detect multiple forms, each enriched in postsynaptic density preparations relative to brain homogenate. Antibodies to 4.1B have been reported to detect two forms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EPB41L2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.63 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene EPB41L2
Gene Accession No. O43491
Gene Alias 4.1G; 4.1-G; AW555191; band 4.1-like protein 2; D10Ertd398e; DKFZp781D1972; DKFZp781H1755; Epb4.1l2; Epb41l2; erythrocyte membrane protein band 4.1 like 2; erythrocyte membrane protein band 4.1 like-protein 2; erythrocyte membrane protein band 4.1-like 2; erythrocyte membrane protein band 4.1-like 2 retinal; erythrocyte protein band 4.1 like 2; erythrocyte protein band 4.1l2 long; erythrocyte protein band 4.1l2 middle; erythrocyte protein band 4.1-like 2; generally expressed protein 4.1; NBL2; OTTHUMP00000040262; RGD1563977; RP3-324N14.1
Gene Symbols EPB41L2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human EPB41L2 (NP_001186317.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2037
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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