Invitrogen™ Ephrin A2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547806

Catalog No. PIPA547806

Description

In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant mouse (rm) Ephrin-A1, recombinant human (rh) Ephrin-A3, rmEphrin-A4, rhEphrin-A5, rmEphrin-B1, rmEphrin-B2, and rhEphrin-B3 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1(Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3(Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. In addition, Ephrin-A2 (Elf-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk).

Specifications

• Antigen: Ephrin A2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EFNA2
• Gene Alias: CEK7L; CEK7-L; CEK7-ligand; EFNA2; Elf1; ELF-1; EPH related receptor tyrosine kinase ligand 6; eph-related receptor tyrosine kinase ligand 6; ephrin A2; ephrin A-2; ephrin A6; EphrinA2; ephrin-A2; Epl6; EPLG6; HEK7 ligand; HEK7-L; Lerk6; LERK-6
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13637
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Neutralization, Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P52801
• Gene Symbols: EFNA2
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Ephrin-A2 Met1-Asn184.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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