Epidermal Growth Factor Receptor (EGFR) Rabbit Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ EGFR, Rabbit Monoclonal Antibody.

Catalog Number	Mfr. No.	Form	Quantity
RM2111R1	Epredia RM2111R1	Ready-to-Use	1 mL
RM2111R7	Epredia RM2111R7	Ready-to-Use	7 mL
RM2111RQ	Epredia RM2111RQ	Ready-to-Use	12 mL
RM2111S	Epredia RM2111S	Supernatant	1 mL

Description

EGFR is a type I receptor tyrosine kinase with sequence homology to c-erbB1, B2, B3, B4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-alpha (TGF-alpha), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, colon, lung, stomach, head and neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Rabbit

Clone: EP38Y

Species Reactivity: Human. Others not tested.

Ig Isotype: Rabbit IgG

Epitope: Not determined

Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human EGFR

Molecular Weight: 175 kDa

Positive Control: Squamous carcinoma

Cellular Localization: Cell membrane and occasional cytoplasmic

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Specifications

• Clone: EP38Y
• Classification: Monoclonal
• Host Species: Rabbit
• Primary or Secondary: Primary

• Applications: Immunohistochemistry
• Conjugate: Unconjugated
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human EGFR