Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

(-)-Epigallocatechin Gallate, MP Biomedicals™

Click to view available options
Quantity:
10mg
50mg
989-51-5
C22H18O11
458.375
WMBWREPUVVBILR-WIYYLYMNSA-N
--epigallocatechin gallate, egcg, epigallocatechin gallate, epigallocatechin 3-gallate, tea catechin, epigallocatechin-3-gallate, --epigallocatechin-3-o-gallate, teavigo, --epigallocatechol gallate, epigallocatechin-3-monogallate
65064
CHEBI:4806
[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
989-51-5
C22H18O11
458.375
WMBWREPUVVBILR-WIYYLYMNSA-N
--epigallocatechin gallate, egcg, epigallocatechin gallate, epigallocatechin 3-gallate, tea catechin, epigallocatechin-3-gallate, --epigallocatechin-3-o-gallate, teavigo, --epigallocatechol gallate, epigallocatechin-3-monogallate
65064
CHEBI:4806
[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O

Inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate, MP Biomedicals is a polyphenolic, tumor-inhibiting constituent of green tea. ECGC is an antioxidant polyphenol flavonoid that inhibits cellular oxidation of low density lipoprote

A natural component of green tea with a variety of biological functions:

  • Bocks the activation of EGF receptors and HER-2 receptors
  • Inhibits fatty acid synthase and glutamate dehydrogenase activity
  • Inhibits the peroxynitrite-induced formation of the oxidative injury markers 8-hydroxy-2-deoxy guanosine and 3-nitrotyrosine, apoptosis in human prostate cancer cells
  • Selectively inhibits activation of JNK/SAPK signaling pathway and suppresses proliferation of vascular smooth muscle cells
  • Shows growth inhibitory effects on tumor cells but not their normal counterparts
  • Inhibits telomerase, a fast-binding and reversible fatty acid synthase inhibitor
  • Inhibits PMA-induced skin thickening
  • Inhibits activation of interleukin-1a mRNA and protein expression
  • Inhibits nitric oxide synthase (iNOS) gene expression
  • At μM concentrations, inhibits VEGF-induced tyrosine phosphorylation
Melting Point 218°C (literature)
Quantity 10mg
Solubility Information Soluble in water (5mg/mL, clear, faint pink colored solution).
Formula Weight 458.4g/mol
Physical Form Light Pink Powder
Optical Rotation −185° ± 2° (ethanol) (Lit.)
Percent Purity ≥95%

Recommended Storage : Store at 4°C.