(-)-Epigallocatechin gallate, Thermo Scientific Chemicals

Description

 

Epigallocatechin gallate is reported to strongly inhibit Cu(2+)-mediated oxidative modification of LDLs. EGCG also inhibits NOS2 (iNOS).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Epigallocatechin gallate is reported to strongly inhibit Cu(2+)-mediated oxidative modification of LDLs. EGCG also inhibits NOS2 (iNOS).

Solubility
Soluble in ethanol, dimethyl formamide, water.

Notes

Specifications

Chemical Identifiers

• CAS: 989-51-5
• Molecular Formula: C22H18O11
• Molecular Weight (g/mol): 458.375
• MDL Number: MFCD00075940
• InChI Key: WMBWREPUVVBILR-WIYYLYMNSA-N
• Synonym: =--epigallocatechin gallate, egcg, epigallocatechin gallate, epigallocatechin 3-gallate, tea catechin, epigallocatechin-3-gallate, =--epigallocatechin-3-o-gallate, teavigo, =--epigallocatechol gallate, epigallocatechin-3-monogallate
• PubChem CID: 65064
• ChEBI: CHEBI:4806
• IUPAC Name: [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
• SMILES: C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O

• Melting Point: 216°C to 218°C
• Color: Orange to Pink
• Quantity: 50 mg
• Merck Index: 143526
• Solubility Information: Soluble in ethanol,dimethyl formamide,water.
• Formula Weight: 458.4
• Physical Form: Powder
• Chemical Name or Material: (-)-Epigallocatechin gallate

Safety and Handling

Hazard Category	H312
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P280-P302+P352-P312-P363-P501c
RTECSNumber	KB5200000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only