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Invitrogen™ EpoR Monoclonal Antibody (C2)
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Catalog No. MA566069
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MA566069 200 μL
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Catalog No. MA566069 Supplier Invitrogen™ Supplier No. MA566069
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Description

Mouse Monoclonal Antibody

EpoR Monoclonal Antibody for IHC (P)

EpoR encodes the erythropoietin receptor, which belongs to the cytokine receptor family. When erythropoietin binds to this receptor, it activates the Jak2 tyrosine kinase, which in turn activates various intracellular pathways including Ras/MAP kinase, phosphatidylinositol 3-kinase, and STAT transcription factors. The stimulated erythropoietin receptor plays a role in the survival of erythroid cells. Defects in this gene may result in erythroleukemia and familial erythrocytosis. Dysregulation of this gene may also affect the growth of certain tumors. Multiple transcript variants are produced as a result of alternate splicing. Diseases associated with EPOR include Erythrocytosis, Familial, 1 and Erythroleukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EpoR
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone C2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene EPOR
Gene Accession No. P14753, P19235
Gene Alias EPO R; EPOR; EPO-R; Erythropoietin receptor; pEpoR
Gene Symbols EPOR
Host Species Mouse
Immunogen Recombinant Erythropoietin Receptor (EPOR) (Pro33-Leu210).
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13857, 2057
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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