Apexbio Technology LLC Amyloid Beta-peptide (25-35) (human)(Synonyms: Amyloid β-peptide (25-35), Aβ (25-35), Beta-amyloid (25-35), Amyloid beta-protein fragment (25-35)), 10mg, CAS: 131602-53-4.

Supplier:  Apexbio Technology LLC A103910

Amyloid Beta-peptide (25-35) (human) (CAS 131602-53-4) represents a neurotoxic fragment derived from the human -amyloid peptide This 11-amino acid segment possesses high aggregation propensity conferring pronounced toxic effects on neuronal cells relative to longer amyloid sequences Mechanistically the peptide promotes neurodegeneration memory impairment and cognitive dysfunction as evidenced by animal models displaying impaired spatial learning and memory following intracerebroventricular administration This peptide segment appears naturally in Alzheimer s disease (AD) patient brains especially within neurons of the subiculum and entorhinal cortex as well as in muscle tissues from individuals with inclusion body myositis As a result A (25-35) serves as an extensively utilized research tool in Alzheimer s pathology studies

Catalog No. 50-000-60415