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Epstein Barr Virus Antibody Cocktail, Invitrogen™

Catalog No. PIMA512172
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500 μL
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PIMA512172 500 μL
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Catalog No. PIMA512172 Supplier Thermo Scientific Supplier No. MA512172

Antibody Cocktail

MA5-12172 targets Epstein-Barr Virus in IHC (P) applications and shows reactivity with Bacteria samples. The MA5-12172 immunogen is eBV-encoded recombinant latent membrane protein.

Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Epstein Barr Virus
Applications Immunohistochemistry (Paraffin)
Classification Cocktail
Clone CS1, CS2, CS3, CS4, CS2, CS3, CS4
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation tissue culture supernatant with 0.09% sodium azide
Gene Alias EBV
Host Species Mouse
Immunogen EBV-encoded recombinant latent membrane protein
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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