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ERF Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A301701AT

Encompass_Preferred

Catalog No. 50-156-1021


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse

ABT1 (activator of basal transcription 1) is a nuclear protein that associates with the TATA-binding protein (TBP) and enhances basal transcription activity of class II promoters. ABT1 associates with TBP in HeLa nuclear extracts in vitro. Another protein, designated ERF, is a member of the Ets family of transcription factors. The members of the Ets family are grouped because they share a highly conserved DNA binding domain. These factors are involved in growth factor pathways and regulate both proliferation and differentiation. ERF (Ets-2 repressor factor) is a ubiquitously expressed Ets-domain protein that exhibits strong transcriptional repressor activity, suppresses Ets-induced transformation and is regulated by MAPK phosphorylation. ERF transcription may be regulated by Ets-domain proteins. Additionally, modulation of ERF activity is involved in the transcriptional regulation of genes activated during entry into G1 phase.
Specifications

Specifications

ERF
Polyclonal
Unconjugated
ERF
PE-2, PE2, ETS domain-containing transcription factor ERF
Rabbit
Antigen affinity chromatography
RUO
2077
4° C
Liquid
Immunoprecipitation
1 mg/ml
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
P50548
ERF
Between 200 and 250
10 μL
Primary
Human
Antibody
IgG
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