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Invitrogen™ ERK1 Monoclonal Antibody (ERK-6B11)
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Catalog No. 138600
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Catalog No. Quantity
13-860-0 100 μg
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Catalog No. 13-860-0 Supplier Invitrogen™ Supplier No. 138600
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Description

Mouse Monoclonal Antibody

ERK1 Monoclonal Antibody for Western Blot, ICC/IF, IP, ELISA

MAPK3 (ERK1) is a serine/threonine kinase that is an important activator of p90, RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. ERK1 is widely expressed and involved in the regulation of meiosis, mitosis, and post-mitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors and transforming agents, activate the ERK1 and ERK2 pathways. Functionally, ERK1 is involved with a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. ERK1 is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms of ERK1 have been described.
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Specifications

Antigen ERK1
Applications ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone ERK-6B11
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene MAPK3
Gene Accession No. P21708, P27361, Q63844
Gene Alias ERK; Erk1; ERK-1; Ert2; Esrk1; Extracellular signal-regulated kinase 1; extracellular signal-related kinase 1; HS44KDAP; HUMKER1A; Insulin-stimulated MAP2 kinase; MAP kinase 1; MAP kinase 3; MAP kinase isoform p44; MAP kinase2; MAPK 1; MAPK 3; MAPK1; MAPK2; MAPK3; Microtubule-associated protein 2 kinase; mitogen activated protein kinase 3; mitogen-activated 3; mitogen-activated protein kinase 1; mitogen-activated protein kinase 3; MNK1; Mtap2k; p44; p44 MAP kinase; P44ERK1; p44-ERK1; P44MAPK; p44-MAPK; pp42/MAP kinase; PRKM3
Gene Symbols MAPK3
Host Species Mouse
Immunogen Synthetic Peptide corresponding to a section of the C-terminus of rat ERK1.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100855877, 26417, 50689, 5595
Target Species Human, Mouse, Rat, Canine
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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