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Invitrogen™ ERLIN1 Monoclonal Antibody (OTI4B1)
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Catalog No. PIMA527097
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100 μL
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PIMA527097 100 μL
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Catalog No. PIMA527097 Supplier Invitrogen™ Supplier No. MA527097
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Description

Mouse Monoclonal Antibody

ERLIN1 Monoclonal Antibody for Western Blot, IHC (P)

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ERLIN1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI4B1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Erlin1
Gene Accession No. O75477
Gene Alias 2810439N09Rik; Band_7 23-211 Keo4 (Interim) similar to C.elegans protein C42C1.9; C10orf69; C80197; endoplasmic reticulum lipid raft-associated protein 1; ER lipid raft associated 1; Erlin1; erlin-1; KE04; Keo4; OTTHUMP00000059425; OTTHUMP00000197867; Protein KE04; Protein KE04 homolog; RGD1307058; SPFH domain family, member 1; SPFH domain-containing protein 1; Spfh1; SPG62; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
Gene Symbols Erlin1
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 107-346 of ERLIN1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10613
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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