ERLIN1 Monoclonal Antibody (OTI4C11), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA809151

Catalog No. 50-168-2604

Description

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.

Specifications

• Antigen: ERLIN1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O75477
• Gene Symbols: ERLIN1
• Immunogen: Human recombit protein fragment corresponding to amino acids 107-346 of human ERLIN1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI4C11
• Conjugate: Unconjugated
• Gene: ERLIN1
• Gene Alias: C10orf69, Erlin-1, KE04, KEO4, SPFH1, SPG62
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10613
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid