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Invitrogen™ ESRP2 Polyclonal Antibody
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Catalog No. PIPA532143
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100 μL
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PIPA532143 100 μL
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Catalog No. PIPA532143 Supplier Invitrogen™ Supplier No. PA532143
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A431, HepG2. Predicted reactivity: Mouse (93%), Rat (92%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing program induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ESRP2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene ESRP2
Gene Accession No. Q9H6T0
Gene Alias 9530027K23Rik; Epithelial splicing regulatory protein 2; ESRP2; PP7059; RBM35B; RGD1310855; RNA binding motif protein 35A; RNA binding motif protein 35B; RNA-binding motif protein 35B; RNA-binding protein 35B
Gene Symbols ESRP2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human ESRP2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80004
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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