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Estrogen Receptor Ab-11 Mouse Monoclonal Antibody, Epredia™

Catalog No. p-4542560 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
Form:
Concentrated
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Form Concentration
MS354P1ABX 100 μL Concentrated 1mg/mL
MS354P1 500 μL Concentrated 200μg/mL
MS354PABX 200 μL Concentrated 1mg/mL
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Catalog No. MS354P1ABX Supplier Epredia Supplier No. MS354P1ABX
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Description

Obtain accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Estrogen Receptor Ab-11, Mouse Monoclonal Antibody.

The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Mouse

Clone: 1D5

Isotype: IgG1/κ

Species Reactivity: Human, Monkey, Mouse and Rat. Others not known.

Epitope: N-terminal domain

Immunogen: Recombinant human estrogen receptor protein

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Specifications

Antigen Estrogen Receptor Ab-11
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1D5
Concentration 1mg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Recombinant human estrogen receptor protein
Quantity 100 μL
Regulatory Status ASR, IVD
Research Discipline Steroids Hormones and Growth Factors
Primary or Secondary Primary
Target Species Human, Mouse, Non-human Primate, Rat
Form Concentrated
Isotype IgG2a κ
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