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Invitrogen™ Ethinylestradiol Polyclonal Antibody
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Catalog No. PIPA175138
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PIPA175138 1 mg
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Catalog No. PIPA175138 Supplier Invitrogen™ Supplier No. PA175138
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Description

Sheep Polyclonal Antibody

Working Concentration: 2.5 μg/mL. Sensitivity: 10 ng/mL Ethinyl Estradiol produces 86% inhibition in a competitive ELISA employing Ethinylestradiol polyclonal antibody.

Ethinyl Estradiol is a semisynthetic alkylated estradiol with a 17-alpha-ethinyl substitution. It has high estrogenic potency when administered orally, and is often used as the estrogenic component in oral contraceptives. Ethinyl estradiol binds to the estrogen receptor complex and enters the nucleus, activating DNA transcription of genes involved in estrogenic cellular responses. This agent also inhibits 5-alpha reductase in epididymal tissue, which lowers testosterone levels and may delay progression of prostatic cancer. In addition to its antineoplastic effects, ethinyl estradiol protects against osteoporosis. In animal models, short-term therapy with this agent has been shown to provide long-term protection against breast cancer, mimicking the antitumor effects of pregnancy. [National Center for Biotechnology Information. PubChem Compound Database; CID=5991].
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ethinylestradiol
Applications ELISA
Classification Polyclonal
Concentration 8.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Alias C20H24O2; Ethinyl estradiol; Ethinyloestradiol; Ethynyl estradiol; Ethynylestradiol
Host Species Sheep
Immunogen Ethinylestradiol(3)-BTG.
Purification Method Purified
Quantity 1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Target Molecule Chemical
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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