Ethyl isonipecotate, 98%

Description

CAS: 1126-09-6 | C8H15NO2 | 157.21 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Suitable for battery materials development.

Applications
It is used as a reactant for synthesis of SMN protein modulators, β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition, nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone. It is also involved in the reactions of RhoA inhibitors for cardiovascular disease therapy and saccharin derived Mannich bases as antimicrobials and antioxidants. It is employed as a reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates.

Solubility
Fully miscible with water.

Notes
Store at room temperature. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 1126-09-6
• Molecular Formula: C8H15NO2
• Molecular Weight (g/mol): 157.21
• MDL Number: MFCD00006003
• InChI Key: RUJPPJYDHHAEEK-UHFFFAOYSA-N
• Synonym: ethyl 4-piperidinecarboxylate, ethyl isonipecotate, piperidine-4-carboxylic acid ethyl ester, ethylpiperidine-4-carboxylate, 4-piperidinecarboxylic acid, ethyl ester, isonipecotic acid ethyl ester, 4-piperidinecarboxylic acid ethyl ester, 4-carbethoxypiperidine, 4-carboethoxypiperidine, 4-ethoxycarbonyl piperidine
• PubChem CID: 70770
• IUPAC Name: ethyl piperidine-4-carboxylate
• SMILES: CCOC(=O)C1CCNCC1

• Density: 1.021
• Boiling Point: 203°C to 205°C
• Flash Point: 80°C (176°F)
• Refractive Index: 1.46
• Quantity: 100 g
• Beilstein: 118419
• Solubility Information: Fully miscible with water.
• Formula Weight: 157.21
• Percent Purity: 98%
• Chemical Name or Material: Ethyl isonipecotate

Safety and Handling

Hazard Category	H227-H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335-H227 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.
Precautionary Statement	P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P370+P378q-P501c
EINECSNumber	214-416-7
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only