Invitrogen™ ETV1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589150

Catalog No. PIPA589150

Description

Immunogen sequence: AFHGLPLKIK KEPHSPCSEI SSACSQEQPF KFSYGEKCLY NVSAYDQKPQ VGMRPSNPPT PSSTPVSPLH HASPNSTHTP KPDRAFPAHL PPSQSIPDSS YPMDHRFRRQ LSEPCNSFPP LPTMPREGRP MYQRQMSEPN IPFPPQGFKQ EYHDPVYEHN TMVGSAASQS FPPPLMIKQE PRDFAYDSEV PSCHSIYMRQ EGFLAHPSRT EGCMFEKGPR Q.

ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.

Specifications

• Antigen: ETV1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Etv1
• Gene Alias: DKFZp781L0674; Er81; ets related protein 81; ETS transcription factor Er81; ETS translocation variant 1; ets variant 1; ets variant gene 1; ETS variant transcription factor 1; ets-related protein 81; Etsrp81; Etv1; MGC104699; MGC120533; MGC120534; MGC137631 protein
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14009, 2115, 362733
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.97 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P41164, P50549
• Gene Symbols: Etv1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-300 of human ETV1 (NP_0049472).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov