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Invitrogen™ EVI1 Recombinant Rabbit Monoclonal Antibody (11H41L13)

Catalog No. PI702005
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100 μg
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PI702005 100 μg
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Catalog No. PI702005 Supplier Invitrogen™ Supplier No. 702005
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Rabbit and Bat Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

EVI1 (MECOM) is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, cell differentiation, and proliferation. It can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. The EVI1 gene can undergo translocation with the AML1 gene, resulting in overexpression of the EVI1 gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EVI1
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 11H41L13
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene MECOM
Gene Accession No. Q03112
Gene Alias AML1-EVI-1; AML1-EVI-1 fusion protein; D630039M04Rik; ecotropic viral integration site 1; ecotropic virus integration site 1 protein; Ecotropic virus integration site 1 protein homolog; EVI1; Evi-1; Histone-lysine N-methyltransferase MECOM; Jbo; Mds; MDS1; MDS1 and EVI1 complex locus; MDS1 and EVI1 complex locus protein; MDS1 and EVI1 complex locus protein EVI1; MDS1 and EVI1 complex locus protein MDS1; Mds1-Evi1; Mecom; MGC163392; MGC97004; myelodysplasia syndrome 1 homolog; Myelodysplasia syndrome 1 protein; Myelodysplasia syndrome 1 protein homolog; myelodysplasia syndrome-associated protein 1; oncogene EVI1; OTTHUMP00000213163; OTTHUMP00000213164; OTTHUMP00000213165; OTTHUMP00000213187; OTTHUMP00000213192; PR domain 3; PRDM3; RUSAT2; zinc finger protein Evi1; Znfpr1b1
Gene Symbols MECOM
Host Species Rabbit
Immunogen Peptides corresponding to Human MECOM (aa 367-384, 901-918).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2122
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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