Invitrogen™ EXOC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532149

Catalog No. PIPA532149

Description

Recommended positive controls: HCT116. Predicted reactivity: Mouse (94%), Rat (94%), Chicken (82%), Rhesus Monkey (99%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.

Specifications

• Antigen: EXOC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EXOC3
• Gene Alias: 2810050O03Rik; E430013E20Rik; EXOC3; EXOC3L; EXOC3L1; Exocyst complex component 3; exocyst complex component 3 like 1; exocyst complex component 3-like 1; exocyst complex component 3-like protein; Exocyst complex component Sec6; I79_024581; KIAA0895L; KIAA0895-like ortholog; LIM/homeobox protein Lhx2 pseudogene; protein Jiangli; RGD1311132; rSec6; Sec 6 homolog; Sec6; Sec6 protein; SEC6L1; SEC6-like 1; Sec6p
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11336, 211446
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.74 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O60645, Q6KAR6
• Gene Symbols: EXOC3
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human SEC6. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov