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Invitrogen™ EYA4 Polyclonal Antibody
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Catalog No. PIPA585694
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100 μL
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PIPA585694 100 μL
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Catalog No. PIPA585694 Supplier Invitrogen™ Supplier No. PA585694
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Chicken (91%). Positive Control: A431, HeLa. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EYA4
Applications Western Blot
Classification Polyclonal
Concentration 1.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene EYA4
Gene Accession No. O95677
Gene Alias B130023L16Rik; CMD1J; DFNA10; dJ78N10.1 (eyes absent); EYA transcriptional coactivator and phosphatase 4; EYA4; eyes absent 4 homolog (Drosophila); eyes absent homolog 4; eyes absent-like protein 4
Gene Symbols EYA4
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human EYA4. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2070
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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