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EZH2 Monoclonal Antibody (AC22), Active Motif™
SDP

Catalog No. p-7188672
Encompass
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Catalog No. Quantity
50-199-2920 10 μg
50-199-2921 50 μg
50-199-2919 100 μg
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Catalog No. 50-199-2920 Supplier Active Motif Supplier No. 39876
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Description

Mouse Monoclonal Antibody

EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Mutations affecting EZH2 can cause Weaver syndrome (WVS).

Specifications

Antigen EZH2
Applications ChIP Assay
Classification Monoclonal
Clone AC22
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene EZH2
Gene Accession No. Q15910, Q61188
Gene Alias an; enhancer of zeste 2 polycomb repressive complex 2 subunit; Enhancer of zeste homolog 2; enhancer of zeste homolog 2 (Drosophila); ENX 1; ENX1; ENX-1; Enx1h; EZH 2; EZH1; Ezh2; EZH-2; EZH2b; Histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; Lysine N-methyltransferase 6; mKIAA4065; OTTHUMP00000213774; OTTHUMP00000213778; OTTHUMP00000213779; OTTHUMP00000213780; WVS; WVS2
Gene Symbols EZH2
Host Species Mouse
Immunogen This EZH2 antibody was raised against a recombinant protein corresponding to amino acids 353-451 of human EZH2.
Purification Method Protein A
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14056, 2146
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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