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F4/80 Mouse, anti-Mouse, R718, Clone: T45-2342, BD OptiBuild™

Catalog No. BDB752152 Shop All BD Biosciences Products
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Catalog No. BDB752152 Supplier BD Biosciences Supplier No. 752152
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Mouse Monoclonal Antibody

The T45-2342 monoclonal antibody recognizes the mouse F4/80 antigen which is also known as EGF-like module-containing mucin-like hormone receptor-like 1 (EMR1). F4/80 is a 160 kDa glycoprotein that belongs to the EGF-TM7 family of seven-transmembrane spanning cell surface molecules. It is expressed on the surface of granulocytes and a wide range of mature tissue macrophages including, Kupffer cells, splenic red pulp macrophages, microglia, gut lamina propria macrophages, and Langerhans cells. F4/80 expression has also been reported on subpopulations of dendritic cells. F4/80 expression is heterogeneous and may be increased during inflammatory responses as observed in various mouse models of colitis, diabetes and brain injury.

TRUSTED_SUSTAINABILITY

Specifications

Antigen F4/80
Applications Flow Cytometry
Classification Monoclonal
Clone T45-2342
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Refrigerate Upon Arrival
Form Liquid
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