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Invitrogen™ FABP3 Monoclonal Antibody (66E2), Biotin

Catalog No. FERMA549043
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50 μg
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Catalog No. Quantity
FERMA549043 50 μg
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Catalog No. FERMA549043 Supplier Invitrogen™ Supplier No. MA549043

Description

Mouse Monoclonal Antibody

The monoclonal antibody 66E2 recognizes human heart-type fatty acid-binding protein (H-FABP) of both natural and recombinant origin.

Fatty acid binding proteins (FABP) are small (approximately 13-14 kDa) intracellular proteins with a high degree of tissue specificity. FABPs are a class of cytoplasmic proteins that bind long chain fatty acids. They are abundantly present in various cell types and seem to play an important role in the intracellular utilization of fatty acids. There are at least six distinct types of FABP, each showing a specific pattern of tissue expression. FABP leaks, due to its small size, rapidly out of is chemically damaged dying cells leading to a rise in serum levels. Liver FABP is a sensitive marker for cell damage of liver cells in vitro and in vivo. Is chemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. Next to this L FABP is a marker for rapid hepatocyte lysis in vitro (as for example in toxicology assays) and for detection of liver damage during and after transplantation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FABP3
Applications Inhibition Assays, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 66E2
Concentration 100 μg/mL
Conjugate Biotin
Formulation PBS with 0.1% BSA and 0.02% sodium azide
Gene FABP3
Gene Accession No. P05413
Gene Alias 422 protein; Cardiac Fatty Acid Binding Protein; FABP 3; FABP11; Fabp3; Fabph1; Fabph-1; Fabph4; Fabph-4; fatty acid binding protein 11; Fatty acid binding protein 11 (FABP11); fatty acid binding protein 3; Fatty acid binding protein 3 heart; fatty acid binding protein 3, muscle and heart; Fatty acid binding protein heart; fatty acid binding protein heart 1; fatty acid binding protein heart 4; fatty acid-binding protein 3; Fatty acid-binding protein, heart; heart FABP; heart fatty acid binding protein; Heart type fatty acid binding protein; heart-type fatty acid-binding protein; H-FABP; M FABP; Mammary derived growth inhibitor; Mammary-derived growth inhibitor; MDGI; M-FABP; muscle and heart (mammary derived growth inhibitor); Muscle fatty acid binding protein; Muscle fatty acid-binding protein; Muscle O-FABP; Mylein protein P2 homolog / adopocyte; O-FABP
Gene Symbols FABP3
Host Species Mouse
Immunogen Purified human H-FABP.
Purification Method Protein G
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2170
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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