Invitrogen™ Factor VII Monoclonal Antibody (9031)

Catalog No.	Quantity
01-676-484	100 μg

Catalog No. 01-676-484 Supplier Invitrogen™ Supplier No. MA143038

Description

Rat Monoclonal Antibody

MA1-43038 detects Factor VII in mouse samples. MA1-43038 has successfully been used in Western blot and ELISA applications. MA1-43038 was derived from mouse factor VII.

Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.

Specifications

• Antigen: Factor VII
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 9031
• Conjugate: Unconjugated
• Formulation: 50% water with 50% glycerol and no preservative
• Gene: F7
• Gene Accession No.: P70375
• Gene Alias: AI132620; Cf7; Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; F7; Factor 7; Factor VII heavy chain; Factor VII light chain; Factor7; FVII; FVII coagulation protein; proconvertin; Serum prothrombin conversion accelerator; SPCA
• Gene Symbols: F7
• Host Species: Rat
• Immunogen: Mouse Factor VII.
• Purification Method: SDS-PAGE
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14068
• Target Species: Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG