Learn More
Invitrogen™ Factor VIII Biosimilar Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA559551

Description
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °. This antibody can also be cross referenced by the term Novo Nordisk patent anti-Factor VIII.
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
Specifications
Factor VIII Biosimilar | |
Recombinant Monoclonal | |
Unconjugated | |
Human | |
100 μg | |
Primary | |
-20°C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance | |
1 mg/mL | |
25mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2 | |
Protein A | |
RUO | |
Human | |
Antibody | |
IgG1 |
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.