Invitrogen™ FAM111B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558474

Catalog No. PIPA558474

Description

Immunogen sequence: SMKTEENKSF SAMEDDQRTR PEVSKDTVMK QTHADTPVDH CLSGIRKCSS TFKLKSEVNK HETALEMQNP NLNNKECCFT FTLNGNS Highest antigen sequence identity to the following orthologs: Mouse - 27%, Rat - 24%.

FAM111B is a 734 amino acid protein that is encoded by a gene that maps to human chromosome 11, which makes up around 4% of human genomic DNA and isconsidered a gene and disease association dense chromosome.The chromosome 11 encoded Atmgene isimportant for regulation ofcellcycle arrest and apoptosisfollowing double strand DNA breaks. Atmmutation leads to the disorderknown as ataxia-telangiectasia. The blood disorders Sickle cell anemia and beta thalassemia are caused by HBB genemutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associatedwithmutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associatedwith defectsin chromosome 11.

Specifications

• Antigen: FAM111B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAM111B
• Gene Alias: Cancer-associated nucleoprotein; CANP; FAM111B; family with sequence similarity 111 member B; family with sequence similarity 111, member B; POIKTMP; Protein FAM111B
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 374393
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6SJ93
• Gene Symbols: FAM111B
• Immunogen: Recombinant protein corresponding to Human FAM111B. Recombinant protein control fragment (Product #RP-97540).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG