Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA5104378

Invitrogen™ FAM35A/FAM35B Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA5104378
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA5104378 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA5104378 Supplier Invitrogen™ Supplier No. PA5104378
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total FAM35A/B.

Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs) (PubMed:29656893, PubMed:29789392). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (PubMed:29656893, PubMed:29789392). Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres (PubMed:29656893). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen FAM35A/FAM35B
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene FAM35A
Gene Accession No. Q86V20
Gene Alias 3110001K24Rik; bA163M19.1; Fam35a; FAM35A1; family with sequence similarity 35 member A; family with sequence similarity 35, member A; protein FAM35A; RINN1-REV7-interacting novel NHEJ regulator 2; RINN2; Shield complex subunit 2; Shieldin complex subunit 2; SHLD2
Gene Symbols FAM35A
Host Species Rabbit
Immunogen A synthesized peptide derived from human FAM35A(Accession Q86V20), corresponding to amino acid residues S393-N443.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54537
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.