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Invitrogen™ FAP Monoclonal Antibody (F11-24), eBioscience™
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Catalog No. 5017837
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100 μg
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Catalog No. Quantity
50-178-37 100 μg
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Catalog No. 50-178-37 Supplier Invitrogen™ Supplier No. BMS168
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Description

Mouse Monoclonal Antibody

Description: BMS168 (F11-24) specifically reacts with Fibroblast Activation Protein (FAP), a cell surface glycoprotein of reactive human fibroblast. Among the normal adult organs tested BMS168 does not show immunoreactivity in immunohistological studies with either resting fibroblasts (fibrocytes) of the normal organ mesenchyme or the parenchymal cells. The single exception noted is a subset of endocrine cells in the pancreatic islets, presumably glucagon-producing A cells. Applications Tested: Flow Cytometry, Immunohistochemistry, Immunoprecipitation.

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.
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Specifications

Antigen FAP
Applications Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Classification Monoclonal
Clone F11-24
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene FAP
Gene Accession No. Q12884
Gene Alias 170 kDa melanoma membrane-bound gelatinase; Antiplasmin-cleaving enzyme FAP, soluble form; APCE; Dipeptidyl peptidase FAP; DPPIV; Fap; FAPA; FAPalpha; fibroblast activation protein; fibroblast activation protein alpha; fibroblast activation protein, alpha; gelatine degradation protease FAP; Integral membrane serine protease; post-proline cleaving enzyme; Prolyl endopeptidase FAP; seprase; Serine integral membrane protease; SIMP; Surface-expressed protease
Gene Symbols FAP
Host Species Mouse
Immunogen Rec. Human FAP.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2191
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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