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Invitrogen™ Farnesyl Polyclonal Antibody
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Catalog No. 01674793
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100 μg
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Catalog No. Quantity
01-674-793 100 μg
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Catalog No. 01-674-793 Supplier Invitrogen™ Supplier No. PA112554
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Description

Rabbit Polyclonal Antibody

Farnesyl Polyclonal Antibody for ICC/IF, ELISA

Isoprenylation/methylation is an important posttranslational lipid modification: the covalent addition of a 15 carbon farnesyl or a 20-carbon geranylgeranyl group to the C-terminus of a protein results in a substantial increase in hydrophobicity. All known G proteins are modified in this way, making the pathway of central interest for an understanding of signal transduction. From nematode to human, many eukaryotic proteins are reported to be isoprenylated. Known prenylated prtoteins include fungal mating factors, nuclear lamins, Ras and Ras-related GTP-binding proteins (G proteins), and the subunits of trimeric G proteins, protein kinases and at least one viral prtoein. Prenylation promotes membrane interactions of most of these proteins, which is not surprising given the hydrophobicity of the lipids involved. In addition, prenylation appears to play a major role in several protein-protein interaction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Farnesyl
Applications ELISA, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.08% sodium azide
Host Species Rabbit
Immunogen Farnesyl cysteine conjugated to KLH.
Purification Method Ammonium Sulfate Precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Target Molecule Chemical
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