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Description
Recommended positive controls: Molt-4, mouse brain, PC-12, Rat2, 293T. Predicted reactivity: Mouse (89%), Rat (89%), Pig (83%), Bovine (85%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Fatty acid synthase is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Specifications
Specifications
| Antigen | FASN |
| Applications | Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7 |
| Gene | FASN |
| Gene Accession No. | P12785, P19096, P49327 |
| Gene Alias | [Acyl-carrier-protein] S-acetyltransferase; [Acyl-carrier-protein] S-malonyltransferase; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-oxoacyl-[acyl-carrier-protein] synthase; A630082H08Rik; Enoyl-[acyl-carrier-protein] reductase; FAS; FASN; Fatty acid synthase; fatty acid synthase (EC 3.2.1.23); MGC14367; MGC15706; OA-519; Oleoyl-[acyl-carrier-protein] hydrolase; SDR27X1; short chain dehydrogenase/reductase family 27X, member 1; thioesterase |
| Gene Symbols | FASN |
| Show More |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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