Fasudil monohydrochloride, 99+%, Thermo Scientific Chemicals

Description

Fasudil monohydrochloride is used in the prevention and treating cardiovascular and cerebrovascular diseases. It is also used in the inhibition of proliferation of vascular smooth muscle cells. It serves as a selective Rho-associated protein kinase (ROCK) inhibitor. Further, it protects against methyl mercury-induced axonal degeneration.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water and dimethyl sulfoxide. Insoluble in ethanol.

Notes
Incompatible with acids, bases and oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 105628-07-7
• Molecular Formula: C14H18ClN3O2S
• Molecular Weight (g/mol): 327.827
• MDL Number: MFCD00943198
• InChI Key: LFVPBERIVUNMGV-UHFFFAOYSA-N
• Synonym: fasudil hydrochloride, fasudil hcl, eril, at 877 hydrochloride, fasudil monohydrochloride, ha 1077 hydrochloride, unii-sq04n8s7br, 5-1,4-diazepan-1-yl sulfonyl isoquinoline hydrochloride, sq04n8s7br
• PubChem CID: 163751
• IUPAC Name: 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline;hydrochloride
• SMILES: C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl

• Color: White
• Quantity: 500 mg
• Merck Index: 14,3942
• Solubility Information: Soluble in water and dimethyl sulfoxide. Insoluble in ethanol.
• Formula Weight: 327.83
• Percent Purity: ≥99%
• Physical Form: Powder
• Chemical Name or Material: Fasudil monohydrochloride

Safety and Handling

Hazard Category	H302
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P264b-P270-P301+P312-P330-P501c
RTECSNumber	HM4031166
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only