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Fc Block , Unlabeled, Clone: 3070, BD

Catalog No. p-4840491 Shop All BD Biosciences Products
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0.25 mg
50 μg
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BDB564219 50 μg
BDB564220 0.25 mg
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Catalog No. BDB564219 Supplier BD Biosciences Supplier No. 564219
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Description

Monoclonal Antibody

FcγReceptors belong to the immunoglobulin superfamily and are expressed at varying levels in multiple cell lineages including high expression in myeloid and B cells. The major functions of Fc receptors are protective functions of the immune system. There are multiple different types of Fc receptors reflecting a variety of different biological activities, which are modulated when they are aggregated by multivalent antigen-antibody complexes.

While normally serving important physiological roles in the immune system, Fc Receptors can also be the cause of nonspecific, false-positive antibody staining of cells. Human BD Fc Block™ is designed and formulated to block or significantly reduce potential non-specific antibody staining caused by receptors for IgG that may be encountered in various applications including the flow cytometric analysis of human cells. Moreover, it can increase the specificity of antibody labeling of extremely rare target cells such as antigen-specific B cells, fetal cells in maternal blood, hematopoietic progenitor cells, or disseminated epithelial tumor cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Fc Block
Applications Flow Cytometry
Classification Monoclonal
Clone 3070
Concentration 0.5mg/mL
Conjugate Unconjugated
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Rhesus Monkey
Content And Storage Store undiluted at 4°C
Form Purified
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For Research Use Only.

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