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FCGR3A Mouse anti-Human, PE, Clone: COC16, Abnova™

Mouse monoclonal antibody raised against human FCGR3A.

Manufacturer:  Abnova Corporation MAB12395

Catalog No. 89-934-131


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Description

Description

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

Specifications

FCGR3A
COC16
Mouse monoclonal antibody raised against human FCGR3A.
In PBS, pH 7.4 (0.09% sodium azide, 0.2% BSA)
CD16/CD16A/FCG3/FCGR3/FCGRIII/FCR-10/FCRIII/FCRIIIA/IGFR3
Mouse
IgG1
50 Reactions
Store at 4°C. Do not freeze.
Monoclonal
Human
Flow Cytometry, Immunofluorescence
PE
Flow cytometry Immunofluorescence The optimal working dilution should be determined by the end user.
Liquid
FCGR3A
FCGR3A
Protein A/G affinity chromatography
RUO
Primary
2214
SDS
Documents
Product Certifications
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