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FCGR3A Mouse anti-Human, PE, Clone: COC16, Abnova™

Catalog No. 89934131 Shop All Abnova Corporation Products
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89-934-131 50 Reactions
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Catalog No. 89-934-131 Supplier Abnova Corporation Supplier No. MAB12395
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Description

Mouse monoclonal antibody raised against human FCGR3A.

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

Antigen FCGR3A
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone COC16
Conjugate PE
Description Mouse monoclonal antibody raised against human FCGR3A.
Dilution Flow cytometry Immunofluorescence The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (0.09% sodium azide, 0.2% BSA)
Gene Alias CD16/CD16A/FCG3/FCGR3/FCGRIII/FCR-10/FCRIII/FCRIIIA/IGFR3
Gene Symbols FCGR3A
Host Species Mouse
Immunogen FCGR3A
Purification Method Protein A/G affinity chromatography
Quantity 50 Reactions
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2214
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG1
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