Invitrogen™ FCRL1 Polyclonal Antibody

Catalog No.	Quantity
PIPA553038	100 μL

Catalog No. PIPA553038 Supplier Invitrogen™ Supplier No. PA553038

Description

Rabbit Polyclonal Antibody

Immunogen sequence: AMWKEDTGSY WCEAQTMASK VLRSRRSQIN VHRVPVADVS LETQPPGGQV MEGDRLVLIC SVAMGTGDIT FLWYKGAVGL NLQSKTQRSL Highest antigen sequence identity to the following orthologs: Mouse - 47%, Rat - 47%.

Fc receptor-like 1 (FCRL1) is a gene situated on chromosome 1q23, encoding a protein that is part of the Fc receptor-like family, which shares structural similarities with classical Fc receptors involved in immune responses. FCRL1 is predominantly expressed in B lymphocytes and is thought to play a role in the regulation of immune functions, particularly those associated with B cell development and differentiation. Although its precise biological function is not fully understood, it is believed to act as an immunomodulatory receptor that could influence B cell signaling pathways. The expression patterns of FCRL1 suggest possible involvement in autoimmune disorders and immune system modulation, potentially contributing to pathological conditions when dysregulated. Research into FCRL1 and other Fc receptor-like proteins continues to explore their contributions to immune homeostasis and potential as therapeutic targets in diseases involving B cell dysfunction.

Specifications

• Antigen: FCRL1
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 0.1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: Fcrl1
• Gene Accession No.: Q96LA6
• Gene Alias: A230020G22Rik; Bxmas1; BXMAS1-like protein 1; BXMAS1-like protein 1b; Bxmh1; Bxmh1b; CD307a; CD307a antigen; fc receptor 1-like protein; fc receptor homolog 1; Fc receptor like 1; Fc receptor-like 1; Fc receptor-like protein 1; Fcrh1; FCRH1DKFZp667O1421; Fcrh1l; Fcrh1s; Fcrl1; FcR-like protein 1; hIFGP1; IFGP family protein 1; IFGP1; immune receptor translocation-associated protein 5; immunoglobulin superfamily Fc receptor, gp42; IRTA5; mBXMH1; mIFGP1
• Gene Symbols: Fcrl1
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human FCRL1. Recombinant protein control fragment (Product #RP-90383).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 115350
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG