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Thermo Scientific™ CpG Methyltransferase (M.SssI)
Description
The enzyme methylates the C5 position on the base moiety of all cytosine nucleotides contained in unmethylated or hemimethylated double stranded DNA in a 5'-CpG-3' context.
M.SssI is specifically formulated for fast reaction times without compromising the reaction efficiency. The enzyme completes modification of all CpGs in 15 minutes at 37°C. In addition, the enzyme has been specifically validated for use with genomic DNA -the primary substrate in epigenetic studies.
M.SssI is supplied with an optimized 10X reaction buffer and 50X S-adenosylmethionine (SAM) as a cofactor.
Highlights
- High efficiency -complete in vitro methylation of all CpGs in non-methylated and hemi-methylated DNA
- Fast -reaction is completed in 15 minutes at 37°C
- Stable -at -20°C for 2 years
Specifications
Specifications
| Enzyme | Methyltransferase |
| Compatible Buffer | 10X Reaction Buffer |
| Quantity | 25 μL |
| Product Type | CpG Methyltransferase |
For Research Use Only. Not for use in diagnostic procedures.
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