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Invitrogen™ Ferritin Polyclonal Antibody
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Catalog No. PIPA5120011
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100 μL
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PIPA5120011 100 μL
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Catalog No. PIPA5120011 Supplier Invitrogen™ Supplier No. PA5120011
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Description

Rabbit Polyclonal Antibody

Positive Control: Rat spleen tissue lysate, human liver tissue, human liver cancer tissue, human kidney tissue, MCF-7, HepG2. Subcellular Location: Cytoplasm.

Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. Ferritin is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in the light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. The ferritin gene has multiple pseudogenes, and ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis. Ferritin is a holoenzyme shell with a molecular weight of about 450 kDa, and consists of 24 subunits of two types, H(heavy) and L(light), and capable of storing up to 4,500 atoms of ferric iron.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ferritin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene FTL
Gene Accession No. P02792, P02793, P02794, P09528, P19132, P29391
Gene Alias apoferritin; cell proliferation-inducing gene 15 protein; Ferritin H subunit; ferritin heavy chain; ferritin heavy chain 1; Ferritin heavy chain, N-terminally processed; Ferritin L subunit; ferritin L-chain; ferritin light chain; ferritin light polypeptide-like 3; Ferritin subunit H; ferritin, heavy polypeptide 1; ferritin, light polypeptide; FHC; frih; fril; FTH; Fth1; FTHL6; FTL; HFE5; H-ferritin; HFt; L apoferritin; LFTD; MFH; MGC71996; NBIA3; OK/SW-cl.84; PIG15; placenta immunoregulatory factor; PLIF; proliferation-inducing protein 15
Gene Symbols FTH1, FTL, Ftl1
Host Species Rabbit
Immunogen Recombinant protein within human Ferritin aa 2-165.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14319, 14325, 2495, 2512, 25319, 29292
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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