Fetal Hemoglobin Monoclonal Antibody (HBF-1), FITC, Invitrogen™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-113-7518	Invitrogen™ MHFH01	500 μL
MHFH014	Invitrogen™ MHFH014	2 mL

Description

Commonly used, FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility. This Fetal Hemoglobin monoclonal antibody specifically recognizes fetal hemoglobin found in fetal erythrocytes.

Hemorrhage of cells from an Rh+ fetus into the circulation of an Rh- mother may result in the formation of Rh-reactive antibodies in the mother. Rh hemolytic anemia in a subsequent Rh+ fetus may result from placental transfer of antibodies formed in the mother to the fetus. Although the volume of fetal erythrocytes found in the maternal circulation during pregnancy and immediately post-partum is reported to be small and of uncertain clinical significance in many cases, substantial hemorrhage may result from a number of causes including fetal or maternal trauma and placental defects. Erythrocytes containing fetal hemoglobin may be found in individuals of any age, but with lower amounts of fetal hemoglobin compared to fetal red cells. These cells have been termed F cells. High levels of F cells may also exist in adults with a heterogeneous group of genetic disorders of uncertain etiology, referred to as Hereditary Persistence of Fetal Hemoglobin. Other clinical conditions causing significant levels of anemia may also result in elevated levels of F cells. Several clinical conditions have been described with increased levels of F cells. These conditions include hereditary anemic diseases such as sickle cell anemia and thalassemia major.

Specifications

• Antigen: Fetal Hemoglobin, Fetal Hemoglobin (HbF)
• Applications: Flow Cytometry
• Conjugate: FITC
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: P69891
• Gene ID (Entrez): 3047
• Immunogen: Human Fetal Hemoglobin (HbF).
• Primary or Secondary: Primary
• Content And Storage: 4°C, store in dark
• Gene: HBG1

• Clone: HBF-1
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with BSA, <10% sucrose and 0.1% sodium azide
• Gene Alias: A-gamma globin; alpha-1 globin; gamma A hemoglobin; gamma globin; gamma-1-globin; Hb F Agamma; HBG1; HBGA; HBGR; HBG-T2; hemoglobin alpha 1; Hemoglobin gamma-1 chain; hemoglobin gamma-a chain; hemoglobin subunit gamma 1; hemoglobin subunit gamma-1; hemoglobin, gamma A; hemoglobin, gamma, regulator of; HSGGL1; PRO2979
• Gene Symbols: HBG1
• Isotype: IgG1
• Purification Method: purified
• Product Type: Antibody