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Genscript Corporation Antibody Protein Proteins Proteins 10 UG 1/EA

Supplier:  Genscript Corporation Z0315510

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Fibroblast Growth Factor-10 (FGF-10) is a mitogen mainly produced by mesenchymal stem cells in lung. FGF-10 belongs to the heparin binding FGF family and is also known as Keratinocyte Growth Factor-2 (KGF-2). It shares homology with KGF and both KGF and FGF-10 activate the receptor FGFR2-IIIb. However unlike KGF which induces the proliferation and differentiation of various epithelial cells FGF-10 is an essential factor for the budding and branching morphogenesis during multi-organ development via mesenchymal-epithelial interactions. FGF-10 is crucial for lung and limb development and is regulated by Shh during early development.

Catalog No. 50-252-9774


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